Strain-relatedness of methicillin-resistant Staphylococcus aureus isolates recovered from patients with repeated infection.

نویسندگان

  • Susan S Huang
  • Daniel J Diekema
  • David K Warren
  • Gianna Zuccotti
  • Patricia L Winokur
  • Shailesh Tendolkar
  • Linda Boyken
  • Rupak Datta
  • Rebecca M Jones
  • Melissa A Ward
  • Tanya Aubrey
  • Andrew B Onderdonk
  • Christian Garcia
  • Richard Platt
چکیده

Invasive disease following methicillin-resistant Staphylococcus aureus (MRSA) detection is common, regardless of whether initial detection involves colonization or infection. We assessed the genetic relatedness of isolates obtained > or =2 weeks apart representing either repeated infections or colonization-infection sets to determine if infections are likely to be caused by previously harbored strains. We found that MRSA infection following initial colonization or infection is caused by the same strain in most cases, suggesting that a single successful attempt at decolonization may prevent the majority of later infection.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 46 8  شماره 

صفحات  -

تاریخ انتشار 2008